Summary: Keyboard shortcuts which use Function keys (F1, F2, F3…etc.) doesn't work in QuarkXPress 10.

Solution:

  1. Quit QuarkXPress.
  2. Navigate to System Preferences > Keyboard
  3. Check the option “Use all F1, F2, etc. keys as standard function keys.”

  4. Close System Preferences.
  5. Re-launch QuarkXPress.
  6. All shortcut commands will now work.

To view keyboard commands, visit : http://www.quark.com/en/Support/Documentation/QuarkXPress/10.aspx